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What is Vardenafil?

Vardenafil is a PDE5 inhibitor medication that helps treat Erectile dysfunction in men. It increases blood flow to the male sexual organ and helps get an erection easier. Vardenafil does not cure erectile dysfunction or impotence or increase your sexual desire. But the Vardenafil tablet may help you assist with a hard erection when sexually stimulated. 

The Food and Drug Administration approved Vardenafil in 2010 as a treatment for Ed. Vardenafil is generally sold under the brand names known as Levitra and Staxyn. Its low-cost generic variants are also available and contain Vardenafil as an active component. 

Vardenafil is a prescription-based drug, and patients less than 18 years of age are not advised to take it. Vardenafil tablet does not protect you from sexually transmitted diseases(STDs) or prevent pregnancy. 

Vardenafil working mechanism

Vardenafil is a PDE5 inhibitor that acts on erectile tissue and blood vessels in the penile area. When a man is sexually stimulated, the release of nitric oxide widens the blood vessels around the penis. When the blood flow increases in these blood vessels, they help the penis to erect and cause an erection. But when an enzyme called Phosphodiesterase type 5 breaks down the cGMP levels, it causes constrictions in these blood vessels. As a result, a man cannot get or keep an erection firm enough for sex. cGMP is another essential enzyme that helps relax the smooth muscle cells of blood vessels and erectile tissue. Thus, inhibiting PDE5 Vardenafil improves the blood flow to the penis and helps a man get an erection easier. 

Note: A man needs sexual stimulation to let Vardenafil assist them in getting a hard erection. Vardenafil tablet does not enhance or increase sexual desire.

Vardenafil dosing information

Vardenafil comes in oral tablets of different strengths, including 2.5mg, 5 mg, 10mg, 20mg, and disintegrating 10 mg. 

The usual initial dose for Adults with Erectile dysfunction is 10 mg orally once a day, as needed. A person can take their ideal dose as prescribed to them an hour before involving in sexual activity. The dosage can be increased to 20mg or decreased to 5mg based on the efficacy and tolerability of a person. 

The maximum dosage amount is 20mg once a day. The effect of the Vardenafil tablet may remain up to 24 hours in the system after a successful intake and action. 

Also, the dosage may need adjustments if you take any other medication that may interact with Vardenafil. The other factors considered for determining dosage can be age, medical history and medical condition. The usual geriatric dose for Erectile dysfunction in age between 65 and older the initial dosage is 5mg once a day. 

How to take Vardenafil?

Vardenafil, as Levitra or form generic drugs, comes in the form of oral tablets. Take the prescribed strength of the Vardenafil pill orally with a glass of water. Swallow the tablet whole in one go, and do not break or chew while taking it. 

But Staxyn(Vardenafil disintegrating tablets) is not used as Levitra or other tablets. It dissolves when placed over the tongue; you do not need to take it with liquid. Use only the form and strength prescribed to you by your doctor.

Vardenafil can be taken on an empty stomach or after a meal. Avoid eating heavy or fat-rich meals while taking Vardenafil, as it may delay the abortion of the drug by your body. 

Take Vardenafil only when needed, almost 30 to 60 minutes before having sexual intercourse. It may take half an hour to kick in and help you get erections for 4 to 5 hours.

Check the expiry date before using the Vardenafil tablets and store them at room temperature. Avoid keeping your medicine in a moist and hot atmosphere. 

What happens if You miss a dose of Vardenafil?

Usually, you need to take Vardenafil as needed, so there are fewer chances of missing a dose.

But if your doctor advises you to take Vardenafil regularly, take the dose in the exact strength at fixed intervals daily. 

But if you forget to take any dose, Skip it as soon as possible if it's almost time for the next scheduled dose. Now take the next scheduled dose at its time and continue the treatment.

 Do not take Vardenafil more than once a day, and take the next intake only after passing 24 hours from the previous dose. 

What happens if I take an overdose of Vardenafil?

Taking a higher or double dose of Vardenafil may cause overdosing effects on the body. You will likely face side effects of this Ed medication, and if you suspect any unwanted effect, please call a doctor immediately.

Overdosing may cause side effects such as-

  • Vision change
  • Priapism(painful or prolonged erection lasting for 4 hours)
  • Irregular heartbeat
  • Dizziness and other unwanted effects on the body

Seek emergency medical attention or call the Poison Help line if the condition appears serious. 

Vardenafil side effects

The common side effects that a person may face while using Vardenafil are-

  • Dizziness
  • Headache
  • Stuffy nose
  • Flushing(redness, sudden warmth, or tingly feeling)
  • Upset stomach 
  • Backpain or body aches

These symptoms are common and disappear as your body adjusts to the medicine. If they persist or become severe, you must inform a doctor.

Some serious side effects of Vardenafil may also rarely appear in some cases. It may include-

  • Sudden loss of hearing or ringing in ears
  • Swelling in your hands, ankles, or feet
  • Seizures
  • Shortness of breath
  • Irregular heartbeat
  • A light-headed feeling
  • Chest pain or pressure
  • Vision changes or sudden loss of vision
  • Painful or prolonged erection lasting longer than 4 hours

Allergic to Vardenafil

Get emergency medical help if you get any signs of an allergic reaction after taking Vardenafil. It may include symptoms such as hives, swelling of the face, lips, tongue or throat or difficulty breathing. 

Drug interactions

Do not use similar Ed drugs such as Sildenafil(Viagra), Tadalafil(Cialis), or Avanafil(Stendra) while taking Vardenafil. Inform your doctor if you take any of the below-given medications before you start taking Vardenafil. 

  • Nitrate-based medications used to treat angina(chest pain)
  • Antifungal medicines(Ketocinazole, itraconzole)
  • Antibiotic drugs(Erythromycin, clarithromycin)
  • Medications used to treat high blood pressure or a prostate disorder
  • Heart rhythm medicines(Dronedarone, sotalol, procainamide, quinidine)
  • HIV/AIDS medications(Ritonavir, atazanavir, cobicistat, indinavir)

It's not the complete list of medications that may interact with Vardenafil. So tell your doctor about all the medicines you take, whether it's a prescription, an OTC drug, taking vitamins, or any herbal products. 

Precautions and Safely measures

If you have allergic to Vardenafil, then you should avoid taking any of its forms prescribed to you. Please discuss with a doctor to get any other alternative to treat your Ed symptoms. 

If you take nitrate drugs for chest pain or angina, you should avoid taking Vardenafil. Interaction among these medications may result in sudden falls in your blood pressure that can be fatal. 

 Consumption of alcohol in excessive amounts while taking Vardenafil can be unsafe. Combined, together can increase the risk of side effects and may impact the ability to get an erection.

Inform a doctor about additional prescription or non-prescription medicines that you take. Also, inform about vitamins or dietary supplements that you have been using. 

Avoid eating grapefruit while using Vardenafil, as it may increase the amount of the drug in the body. As a result, a person is more likely to face side effects of this Ed drug. 

Before you take Vardenafil, you must inform your doctor if you have the following medical conditions. Using Vardenafil under these conditions can be unsafe and may require special caution. Also, your doctor may ask you to avoid its use due to health concerns.

  • Cardiovascular disease, heart rhythm problems
  • Had a heart attack, congestive heart failure, or stroke
  • Have high or low blood pressure problem
  • Seizures
  • Long QT syndrome(in you or anyone from a family member)
  • Blood cell disorder (Multiple myeloma, sickle cell anemia, or leukemia)
  • Suffering from bleeding disorders such as Hemophilia
  • Hearing or vision problem 
  • Retinitis pigmentosa is an inherited eye disorder
  • Active stomach ulcer
  • Physical deformity of the penis or Peyronie's disease
  • Liver disease or kidney disease 
  • Restricted from sexual intercourse by a doctor due to health concerns

If you experience dizziness or drowsiness after taking Vardenafil, do not drive. Better you wait and stay indoors until you start to feel alright and safe.

Females are not advised to use Vardenafil, so they should not take it during pregnancy or breastfeeding. 

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